Imaging frequency and dosimetric sampling: Serial imaging to capture kinetics may be limited by logistics and patient burden; sparse sampling requires modeling assumptions that introduce uncertainty.
The MIRD-237 report is based on a thorough examination of existing literature, data analysis, and expert opinions. The methodology used in this report includes: MIRD-237
Image registration and segmentation: Aligning functional images with anatomical CT or MRI, and segmenting organs, tumors, and background regions for region-based analysis and for deriving voxel-level activity distributions. Imaging frequency and dosimetric sampling: Serial imaging to